Library · paper

Historia de los ensayos clínicos aleatorizados

Graciela Demirdjian
2006·Asociación Argentina de Pediatría — Programa de Actualización Continua

Source: https://www.sap.org.ar/docs/publicaciones/pronap/2006/PBE-HistoriadelosECA-AAP2006.pdf

A Spanish-language history of randomised clinical trials — from James Lind's 1747 experiment on scurvy to the twentieth-century institutionalisation of the RCT as the gold standard for medical evidence.

Demirdjian writes accessibly for clinicians and the piece is short, but the historical texture it offers is valuable: the RCT is a young practice, contested at every stage, and its extension to non-medical contexts is a cultural choice more than a logical inevitability.

For product direction it is useful background for anyone thinking seriously about A/B testing and causal inference — knowing where the method came from clarifies what it can and cannot do.

A short paper, worth its length.